Abstract Background Pituitary neuroendocrine tumors (PitNETs) are one of the most common types of intracranial tumors.Currently, the cellular characteristics of normal pituitary and various other types of PitNETs are still not completely understood.Methods We performed single-cell RNA sequencing (scRNA-seq) on 4 normal samples and 24 PitNET samples
Tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) significantly improve the outcomes of patients with Nail Forms advanced clear cell renal cell carcinoma (ccRCC); however, high-grade toxicities can occur, particularly during combination therapy.Herein, we report a patient with advanced metastatic ccRCC, who developed grade 4
Virendra Rambiritch,1 Poobalan Naidoo,2 Breminand Maharaj,1 Goonaseelan Pillai3 1University of KwaZulu-Natal, Durban, 2Department of Internal Medicine, RK Khan Regional Hospital, Chatsworth, South Africa; 3Novartis Pharma AG, Basel, Switzerland Aim: The aim of this study was to describe the pharmacokinetics (PK) of glibenclamide in poorly cont
Background Modified Bishop score (MBS) and cervical length determination by transvaginal sonography (TVS) are the two methods for predicting successful vaginal delivery based on pre-induction favourability of the cervix.Aims and Objectives This study compared both methods for predicting successful vaginal delivery.The primary objective was to compa